The one advantage you get with the R2S is the 50f3.5 Heliar. The camera is not really a "collectible" (few cameras are and then usually because they are nicely designed, but ergonomic disasters, Prominent, Robot, Exacta etc). The Heliar is one of the few new lenses that I know of that deserves its legendary status!
I have the R2S and I use it with what I call "non-standard" film - i.e films that are not 400 asa - as it stops me from needing to re-calculate in my head. The finder is one of the best available, the range of available framelines makes it useful, a 35/50/85 covers a lot of ground. Personally, I tend to use it with the 85 (and 105 -inside frame lines work here) as the finder on the S3 is a bit confusing with all frames showing at all time - and the SP is incredibly cluttered with 85/105 dialed in.
My biggest problem with the R2S is that it can't take Nikon re-loadable cassettes. Mechanically I have had no problem with it (and over 10 years I have only had one Bessa act up - a R2 decided to only show one "arrow" for exposure - but one of my M6's does the same thing).
It might not feel like a 50's (or repro) Nikon - but it is a camera for using and as such very convinient.
It will end being a camera that once sold out - it will become desirable and probably hold or increase in value as the late-comers decide that they need one.