About a year after my wife and I got married, we took a driving trip from Ft Knox to NW Missouri, up through Nebraska, South Dakita, Wyoming, then cut a corner of Montana and Idaho (via Bear Tooth Pass), down to Yellowstone, the Salt Lake City, several scenic sites and canyons to the North Rim of the Grand Canyon. Then to the Four Corners, which I found fascinating (Mesa Verde), through Wolf Creek Pass to Colorado Sprints, across Kansas to Missouri again, and returned to Ft Knox. We traveled by VW camper. A tough but fascinating trip. I wouldn't recommend it to any but the most hardy. We were younger then.
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But since you are in that part of the country, depending on what you want from your vacation, you might consider a side trip to the Four Corners and environs.
http://www.nps.gov/grca/planyourvisit/directions.htm and
http://wiki.answers.com or google "How_many_miles_away_is_the_Grand_Canyon_from_the_four_corners_monument" to see if it seems too arduous for you. I get the impression you are looking for some just goof off time and take it easy time for your vacation, and there's certainly nothing wrong with that.
Regardless of what or how you do it, I think you will enjoy that area and be glad to have vacationed there.
As to gear, it depends on what you anticipate from your photographs. I took my Fujica ST 901 and a variety of primes and zooms (including an 18mm and a 24mm, as well as a 28mm, 135mm, and 80-200mm zoom), as well as a Super Press 23 (only at standard 100mm lens and a 65mm wide at the time). I found that worked well for me, but then again, I was traveling in a vehicle. But I really like the MF photos I got. YMMV. But whatever, I look forward to seeing your photos and hearing how you two enjoyed wherever you end up going.