I did a quick "test" if you can call it that. I used my stash of 21's and shot a couple of rolls with each one. Mainly 100 asa films as those tend to give you a bit more information.
Here it goes:
21/3,4 Super Angulon (very late # 2.9xx xxx). Still one of my favourites, but mainly for sentimental reasons. I have had a 21 SA since they came out in 1964. Then it was a stellar lens. Very sharp centre performance, but distinct fall off in the edges. Today it is a decent lens with a 'signature" to it. center sharpness is still among the best available, but it is not up there with the rest anymore.
21/4 VC LTM: This lens was sensational when it came out. A $400 package with the finder and it was and is still a formidable lens. Yes, it is a stop slower than Leica and Zeiss's newest, but unless you are planning to do "mega" blow up's, it will serve you well. The flexibility of being able to use it on LTM and M bodies is attractive too.
21/4 P VC: This is the 21VC in a dedicated M mount. If you are strictly a M user it is a good deal, though you dont get a finder with it anymore. The aperture ring is easier to get a grip on than on the LTM mount version. Performance is the same as the LTM version which means excellent. It is a remarkably distorsion free lens - actually better than the 21/2,8 Asph from Leica in this aspect.
21/2,8 Asph Elmarit: I had one of these for many years and though I cant complain about the performance, it is BIG and rather clunky to use. Nice, even rendition, but with typical Leica Aspherical harshness to the image and rather high contrast. More distorsion than the VC 21 or the Biogon 21/4,5
Biogon ZM 21/2,8: I like the Zeiss line of lenses for several reasons. One is that, although not small, they are smaller than the Leica equvivalents and that the contrast and "tone" of the lenses is the same from the 21 up to the 50mm lenses. When you look at negatives the tonal rendition is the same across the board, only the angle of view is changing. This is quite a remarkable feat in consistency. Resolution and distortion is similar to the 21/2,8 Asph from Leica although the slightly lower contrast makes it look "softer" but I think that is deceptive and i would use either one without any hesitation.
Biogon 21/4,5 ZM: Very nice lens. It has the same tonality as the rest of the ZM lenses and based on the 20-25 rolls so far, it is up there with the best of them when it cames to resolution. Where it really shines is in the almost total lack of distortion, it is something in the order of 0,14% which is negligble for all practical purposes. Considerably smaller than the 21/2.8 ZM. Same diameter barrel, but shorter. The 46mm filter size and bayonet is the same as the 2.8 and you can use the 21/2,8 hood with it. On the Bessa R4M I prefer to use it with the 25 ZM hood instead as it prtrudes less in the R4 finder.
Biogon 21/4.5 (1957) Contax/Nikon mount: It was a classic lens in the 50 and 60's and the Biogon formula has always been the top formulation for distorsion free images (Think Hassselblad SW/SWC with its 38mm Biogon!). I remember shooters carrying a Contax or Nikon just for this lens, while everything else was Leica M! It is an ergonomic disaster, minute engravings on chrome and HEAVY and finding a hood that both worked and stayed on was a challenge.
Ricoh 21/3,5 LTM: I have one of these rather scarce lenses and mine is even in black! Good lens, but not even close to the 21/4VC. Quite a bit of fall off and a weird arrangement for setting aperture and focus. A small protruding lever for the aperture ring which keep fouling up your finger when you try to focus and usually end up either shooting stuff 1 stop over or under by mistake.
Which to pick? It depends what you want to do with it. The 21mm focal length tends to be a bit of a special event lens. Unless you are in crammed asian or european cities, it is usually too wide for street shots and it is not flattering for people , particularly if they are close to the edge of the image. It is great landscape focal length and also for "city scapes". If you do commercial work and need straight lines for architectural, either the VC 21 or the Biogon 21/4,5 would work well (i assume that if you shoot this kind of stuff, you use a tripod and most likely would be stopping down to f11 or 16 anyway). If you do interiors and you are mainly hand holding, the 2.8's would do well though I have always felt that on a 21 or wider, speed is less of a problem than even illumination and overall image quality.
If you already have the 21/4 VC in LTM mount, be happy and keep shooting. If you are looking for a 21 and are willing to spend a little look for the 21/4 P, if your budget allows a bit more look at the 21/4,5 ZM or the 21/2,8 ZM (the latter if you are a slow color film shooter where 1 stop can make a difference) and if you just won the lottery or inherited chunks of money and like to carry large. bulky objects, look at the 21/2,8 Asph Elmarit.
All of these lenses will do you well. There is not that much distinction between them for my style of shooting (mostly handheld, asa 100 to 400 bl/w processed for printing rather than scanning) so my choice comes down to ergonomics and weight as well as performance. I rarely print larger than 11x14 and with wide angles tend to shoot around f8-11 when I can.
At the moment, I have been using the 21/4,5 ZM more than any of the other, but that is also because it is new to me. I suspect that it will remain more or less welded to my R4M, but that does not mean that I will not take any of the others out for a spin. Particularly the 21/3,4 Super Angulon as it is my "flash back" lens. Tri X/M2/21f3.4 - how 60's can you get!