I think its ambitious indeed. The big question is how do you show this visually? Maybe you need text with the images. It could involve hundred of photographs. Maybe more but I think if you find a place to start maybe it takes on a life of its own but the important part is starting.
When I read all of Gordnon McDonald's "questions of life", a lot of them relate to identity, relationships, and finding our place in the world. Perhaps it's enough to juxtapose things in the context of life's passage, and all of these questions would be aroused in the viewer?
Here's one seed of an idea. I went through my pictures in the gallery to find anything that had wheels in it...
A young boy, aspirational... seeing what he can do at the skate park )wheels)
A "P Plater" driving a vintage car (wheels). Is it his father's car. What kind of man will he grow to be? Will he be like his father?
Young men on Trikes (wheels). Their kind of too old for this activity, but it doesn't matter because they belong to the pack. They are still connected to the notion of wheels as "fun".
A man at the bus stop, looking kind of dishevelled like the shopping trolley beside him (wheels). He's alone. Does he have a wife or family, like the woman at the distant intersection with the stroller (wheels)? Why are some people winners, why are some losers?
A car as a symbol of freedom, possibilities, exploration.
A similar symbol of freedom, albeit a single man's freedom.
An elderly mother caring for her adult disabled son (wheelchair). Symbolic of life's long burdens.
A different relationship to wheels in old age, accompanied by the indifferent gaze of a young glamorous woman on the poster.
The fate of earthly bodies. How will I die?