It could be, that your scanner settings are incorrect. In Vuescan, scan as B&W film, choose Tmax 400 and CI 0.40, look at the preview, and try to avoid getting the blank spaces into the frame, i.e. after the first preview, adjust the frame, so that only exposed part is chosen, and redo the preview, just to make sure. Your histogram should be extended over most of the available space, with the right end touching the zero level - if it escapes up, then the neg is too dense, and you need to try scanning as colour negative or even slide film. Also, make sure ICE is turned off. Looking at this last negative, it almost appears like you have exposed it to some light, the shadows are not clear. Are you sure, your exposure is ok ? What camera was that ?