I almost always reduce noise although in well lit scenes und using a reasonable ISO setting its admittedly pretty unnoticeable in most cases when viewed at less than full size. But it is still noticeable if you enlarge the image to 100% and look closely (and know what you are looking for) so I prefer to get rid of any that is there.
Noise is very often made more noticeable by subsequent PP steps!!!!!
For example sharpening can make noise more apparent. And even worse, if you use local contrast / micro contrast filters (however named in different software) those processes REALLY bring out noise quite badly. So it makes sense to get rid of it up front.
I have a more or less standard workflow - NR, tonal and brightness adjustment, color and saturation adjustment and lastly sharpness adjustment. All photos get more or less this sequence although the amount of each filter changes from shot to shot. (Some photos get more especially if I want to apply special effects.)
My mantra is that good results in photography is mostly about taking pains. Making sure verticals are properly vertical (or horizontals are horizontal) making sure that there are no blown highlights, that color is correctly balnaced, that sharpness is good etc. And of course this means getting rid of unnecessary noise.
I have good software that seems able to make its own intelligent decisions about how much noise reduction to apply in most cases - especially where noise is limited. This means that image resolution / sharpness seldom suffers when the software is left to its own devices. It is also able to apply NR selectively to areas where its needed (eg to darker areas) leaving other areas untouched, so that helps. Of course there are times when say an image is badly exposed, that NR will reduce image res. as there is too much noise requiring too much NR to get rid of it. Then its hard - choices need to be made between how much noise is acceptable compared with how much resolution loss.
I believe that if you want to become a better photogrpaher, often it means becoming a bit "anal" about such issues. (Assuming of course that your artistic skills are up to it and that your basic image is interesting.)