If it can be done with film, then it can be done with digital. It may not "feel" like though, IMHO, due to the disposable/duplicate-able nature of digital and maybe strange feeling of a lack of authenticity.
I think that there is no difference between film's ability to contain "art" or a file on a computer, but it's hard to imagine a time when someone buys an original photo at Sotheby's or the like for £100k, and the auctioneer requests an email address to send the file to. Or perhaps you just get an FTP login to download your purchase.
A print and a negative at least has a uniqueness.