Don't forget Xcape, LA is only a hope skip and a jump from Portland by air, train and car.
Portland has a high cost of living for its size, but you'll be pleasantly surprised compared to what the scene is down in Cali.
I'm originally from California as well...and have been back many times. It's a crazy joint down there, and I've gotta say, LA is my least favorite city in the WORLD. Money's money on the other hand, and it wouldn't be that hard for you to set up shop in Portland, and use the money you'd be saving in rent or mortgage to fly down to LA and drive up to Seattle to drop your stuff off at galleries or buyers.
And let's not forget that Oregon has some of the most diverse and scenic nature in the world...plenty of fuel for art prints.
I'd be happy to show people around....anybody that's coming out, just give me a holler.
I forgot to mention, there are a couple good photo shops...some are good for some things, and not others obviously. Citizen's Photo is great for used gear like enlargers, chemicals, etc. Plus they have the best lab in town, as far as I've experienced. Optical prints, hand dunking, etc. etc. etc. But their service can be...somewhat less than great from time to time. They've especially got this one bearded curmudgeon behind the camera counter that although knowledgeable, is one of the biggest asses this side of Bhutan.
Then of course Prophoto is a good shop. They've got a mountain of film, and just about any camera you'd like. The staff is very knowledgeable, but their prices are not the best around.
Cameraworld USED to be a great shop, but now it's Ritz camera's little bitch. It looks like a huge shopping mall store now, with all the photo albums, $20 tripods and digital dropboxes you could possibly want. I don't think they even do their own labwork anywmore, which used to be exceptional, reasonably priced, and FAST.
A surprsie to a lot of people is Shutterbug downtown. Shutterbug is an Oregon chain of photo stores, most of which aren't anything special...shopping mall kind of stuff. When they moved their downtown store one block into a nicer building, they made it their flagship store, and they became a Leica dealer; they also carry a bunch of other stuff, like Canon XL series video. It's not a big store, but it's got good staff, good prices, and it's centrally located. A nice little gem, as far as I'm concerned. I've heard they do good printing as well, but I don't know personally.
I should also mention, one of the biggest reasons to choose to live in Portland or Seattle is the nature....my wife and I should've moved away a couple of years ago, and before long we will, probablly to Europe. Why we've stayed however is that it's just too nice of a place to easily let go.....five minutes to the Willamette, and I can kayak to my heart's content. 15 minutes and I'm at either of two magnificent salmon and steelhead streams, 20 minutes and I can catch a monster sturgeon, and an hour and ahalf, and I'm at some of the nicest beaches in the world. (but the ocean is COLD here) And of course 45 minutes to one hour, and you can ski nearly year round.....
Even on DIRTY days, the air here is much cleaner than California. I long ago discovered that only native Angelinos can smell that particlular air in LA, a mix between the sweet jade plants and car exhaust...nobody else seems to notice it down there. Up here every day smells different...fresh rain, new rain, old rain, roses, rivers, grass.....not to mention once in a while the ocean air comes up the columbia, and you feel like you're seaside. Seattle is a wonderful city too, and MUCH bigger, but very very crowded, and with a lot more homeless people.
All the benefits of Portland have their drawbacks though, as with all things in life. Especially as an art photographer, you might have some trouble...there's a lot of galleries, and some of them even draw high prices, but they're not New York or LA prices, I'm afraid. A lot of people end up selling their wares at Saturday Market, which can be handy for somebody who needs "just enough" money, but I can think of a couple of guys at Saturday Market that make some really fine work, and just struggle to get by.
But once again, I have to say....a wise move would be to base yourself in Portland, and sell your stuff all around the country, and even the world. The Portland scene will give you some love, but the other places will give you money.