I don't think the newer versions of PS are user-hostile at all. In fact, I find CS5 incredibly simple to use and it has some tools that are real time-savers. Spot healing, which was introduced in CS4 and especially content-aware spot healing, which was introduced in CS5 are incredibly useful for removing dust from scanned negs. Also, the quick selection tool and refine edge in CS5 have proven to be quite useful for me in a recent job I did. It was a small product shoot and I agreed to do the retouching (cutting products out from the background) myself for an additional couple hundred dollars as the budget was tight. That function alone saved me a lot of time and tedious manual labour.
That being said, for my personal work I hardly ever need to do much in PS as I can do most of what I want in Camera Raw, which, I suppose, has the same editing functions as Lightroom. I've tried Lightroom and Capture 1 but these programs get on my nerves with their file handling. Especially Capture 1 as it creates its own folders whenever I open a file with it.