In theory, the fewer constraints the lens designer has, the better the optical quality s/he can deliver. In practice, there are always some constraints (such as size, weight and cost) so loosening up other constraints makes it easier for the designer to do a good job.
The amount of rear intrusion (distance lens can protrude into camera body) is definitely a design constraint: with SLRs the rear intrusion has to be limited to avoid interference with the mirror. With an RF this dimension is more flexible, giving the designer more freedom to deal with other constraints.
Since RF optics tend to be premium priced, this greater design flexibility seems to show up not so much in the form of wilder specs as in the form of higher quality. To pick one trivial example, my 21mm f/2.8 Kobalux RF lens has much better full-aperture performance than my 20mm f/2.8 AF Nikkor (and is considerably smaller as well.) I can only speculate as to why, but one good guess is that since the Kobalux designer didn't need to worry about providing clearance for a reflex mirror, s/he was able to make a more favorable compromise on the other constraining factors of the design.