Answers will vary based on operating systems. On a my Mac, SuperDuper or ChronoSync work very well for local back up. I use both; SuperDuper for entire system and all files back up and ChronoSync for specific folder back up. I don't us a PC so I don't have any recommendations for that OS. The most important thing for me is automation. I have my system set to back up automatically every night. The most data I will ever loose is yesterday's work. I never have to remember to do it, it, I don't habe to think about it, it just happens automatically. And. If I feel like I can't loose what I just saved, I can always initiate a back up anytime. Best back up advice "3-2-1" 3 copies, 2 local, one on the computer and one on the back up and a third off site.
Hope it helps.
Dave