I'd second this. Have been using a Bowery for over two years now. It's traveled the world with me and I love it. Tried the Filson Field Camera bag for a trip to Fiji and it was quite big and hugged the body, but too floppy, offered too little protection, and it folded it on itself making it difficult to get things in/out of the bag. Have a Hadley Pro and it can hold a massive amount of gear, but is also on the stiffer side. The Domke FXA and FXB bags I own are nice and simple, but the velcro is annoying as hell.
My go-to travel bag will continue to be the Ona Bowery.
Not pictured - external battery pack and batteries for the Fuji which fit next to the film case in the center, ND/Orange filters which fit in the front pocket, and an iPad Air which can fit in the rear slot. For such a small bag, it can fit a lot of stuff when you need it to.