I lived in Newport for many years and consider the following sites worthwhile. If there is any swell on the ocean, consider Depoe Bay to view the "Spouting Horn". Watch the spout from a distance before taking your camera close. Most action on a rising tide. Approx 20 miles north of Newport.
The" Lookout" viewpoint. Depending on the weather (fog), some great vistas. Approx 5 miles south of Depoe Bay.
The Devils Punchbowl State Park at Otter Rock, about 2 miles south of the "Lookout". At low tide, you can walk among the tidal pools and view marine life. Approx 9 miles noth of Newport.
Newport: Moes, go to the "original", not the annex. Usually long lines.
Across the Yaquina Bay bridge, at South Beach, tour the national award winning Rogue Ale Brewery. A fun tour and good restaraunt if Moes is too busy. Nearby, there is also the aquarium, former home to Keiko the killer whale. A really great exhibit is the" walk under the sea" in Keikos' former home. You walk thru a huge underwater plastic tube and can see all sorts of fish, sharks, salmon, halibut and countless others.
Then south on #101 to The Sea Lion Caves, a mainland rookery. You should get some good shots there.
You can continue south on #101 for a spectacular drive to the Redwoods, or turn inland at Reedsport and follow the Umpqua river to Roseburg and go directly to Crater Lake from there. This is also a beautiful drive. A lot of miles, but Oregon is a large and very scenic state.
If you have any questions, I would be happy to give more specific details.
Have a great trip.
Gerry