Software is not the problem. Consumer grade scanner is. Unfortunately the reasonably priced medium priced scanners are no longer made, ie Nikon , Minolta 5400 series.
Other peoples settings are of no value because it is a custom adjustment. First get the film flat. then adjust the height to get the sharpest possible point. I would put one end at zero and the other at max. Then scan the whole strip to find the sharpest area . Say you went from zero to 6 and the middle was best which was 3 in theory. Then repeat 2 at one end and 4 at he other to fine tune..
All digital files need to be sharpened and you now have a digital file. That is what Nik sharpener pro is for or Photoshop. Do a base sharpening, then burn/dodge, adjust contrast, reduce to final size and resolution, then do final sharpening.
Use the scanner software to produce a correctly exposed file. All else needs to be done in a program made for that.
You will need to learn and apply all techniques digital photographers use specially sharpening. Those settings are specific to subject, print size, and resolution, and paper type.
If you do everything correctly, you should be able to make 8x10 as good as an optical print. Some place around 11x17, you will need a better scanner.
A good scan will find things that you never saw in an optical print. Be prepared to retouch.
Glossy ink jet papers are sharper. Lazer printers like Durst Lambda like around 240 ppi.
Search the internet for tutorials on sharpening. It is much to complicated to explain fully here.
http://www.ronbigelow.com/index-2.htm
is a very good site