i have a hadley small and a domke f6. i take the f6 everyday to work with a x100 and maybe a folder, a vivitar ultra wide and slim or a bessa-l with 15/4.5, camera wise. i have the front pocked loaded with batteries, film, microfiber cloth, paper tissue, sanitising gel, chewing gum and some printed photos if i bump into someone i took a photo of.
i like the (over) empty space because i can also fit an umbrella, a water bottle or a rolled up light cardigan into the bag.. sometimes i end up going someplace else after work like the japanese neighbourhood, and with the empty space i can tetris some groceries in, and it's pretty amazing what one can fit in the f6!
i've been taking the hadley small out when i go shooting with a camera and 1 or 2 extra lenses, or just the x100 with some spare space (in summer, because during winter i'll just have the x100 into a jacket pocket).
ive been considering getting a hadley pro or large, i really like the slimmer profile of the hadleys and itd be good to be able to have more than what i can fit on the small, also the quality is pretty amazing. i do like the grip on the domke strap though, makes one shoulder carrying much more positive - though i usually have it crossed around my chest anyway.
i still dont have a basic kit for each bag, so whenever im gonna take the hadley out i'll move everything relevant to it, then take out when im back.