I have the 4180 since 6 months. First scanner ever so nothing to compare with.
I started to scan through a lot of old slides and I´m pretty satisfied. Sure quality suffers on the way from slide to pc to inkjet print but less than I expected.
Now I mostly scan B&W negs and it works OK. I scan them straight (48 bit color) and work them in PS. I have also tried some c-41 b&w anc compared neg to print scan. See no difference.
Most annoying have been scanning of mf-negs. The Epson mf-holder makes me go crazy. I have ordered Doug´s mf holder and expect an easier life.
I have turned to straight scanning without adjustments pre-pc, otherwise the scanning takes oh so much time. A 35 neg with dust reduction, unsharp mask and color fixing can take as much as 10-15 minutes!
A b&w neg, no adjustments, 48 bit color, max resolution 3-4 minutes.
All in all, it´s cheap, delivers ok scans but, scanning, and this is not against the 4180 but in general, is the boring, boring side of photography