Chris :
The Bronica does certainly have close focus issues. It will not allow you to get any closer than 1m (which is generally just fine in my experience), but it will not be like something with bellows focus . . .the cambo, for instance. But, there really is nothing MF handheld that allows close focus . . . not sure about the Plaubel Makina or the Pentax 67. I mean I can't think of anything. An RZ67 is kind of hand holdable, but it is unpleasant.
All of my portrait work has been with cameras shooting at 1m minimum focusing distances, and I have never had a problem getting tight shots (but that WAS with an 80mm lens). The 65 is super sharp and very flat, so cropping is easy. Generally, I dislike shooting tightly framed portraits, because I need cropping flexability most of the time. I find a sharp/low grain film, a good shop, and crop down when necessary.
I plan on shooting my next set of a model with my RF645 and the 65mm lens.