"When you scan a film with a dense base, it requires more light to pick up detail, and the scanner doesn't usually like that."
Do the scanners use this? I think they use always the same light.
"I may be totally wrong, but that's what I remember reading. Also when you scan, you can choose where on the histogram to scan, so most of the 'accuracy' is decided by you, and what you want from the neg."
Well, but that is only a post-processing issue. You are not getting more detail/information from the area in the histogram you decided to scan. I think....
Film physical properties profoundly affect scanning results. Most scanners use a fixed amount of illumination. This is the reason why differences in films occur.
The scanner light color temperature is also relevant as different films could respond differently to light with different color temperatures. LED scanners deliver more constant light over their lifetime as the bulb characteristics are less affected by aging.
To simplify the discussion let's think about transparency film.
Suppose the scanner light illumination is insufficient to adequately represent (model) the shadow regions in film with a dense base. Information from the unilluminated film regions is not present in the data. No amount of post-production trickery can recover data that never existed.
The scan histogram means nothing. No setting can add data that was never collected! A nice looking histogram only describes the information content that was digitized. [1] Information lost by inadequately lighting the source is not present; can not be known; and can not be recovered.
However, the exact same scene using film with a thinner base will pass more light which increases the overall information content.
For these reasons this why optimum exposure and development decisions for film that will be scanned can be different for film that will be printed using a pure analog process.
1. This is also the motivation for using scans that generate raw data. No information is lost due to lossy JPEG or TIFF compression. No information is lost due to non-optimum, but well meant, JPEG or TIFF rendering parameters. A fundamental tenement of information theory is to retain as much data as possible. Scanning with compression and rendering parameters applied destroys some of the original data. In some cases the lost data in uninformative. This is not always so. The time to discard uninformative data is during rendering of the raw scanner data. Some scanner software supports the generation of flat demosaicked data. The data can be in TIFF or DNG format. In both cases irreversible changes in the original data due to applying \ demoasicking parameters such as white balance, relative channel scaling (contrast and curves) and sharpening during scanning are avoided. Instead image rendering is optimized during post-scanning rendering.