APS-C has once again become my standard digital format. It works well for me in current cameras with modern 24 Mpixel sensors like the Leica CL, and does particularly well as focal lengths go longer, from 28mm up. This is because fast but compact and light-weight lenses are easily doable in the 35-200mm range; it is also nice because it nets more DoF at a larger lens opening, useful for use with longer lenses. I'd prefer 3:4 format proportion over 2:3 (18x24 rather than 16x24 mm), but that's a minor, personal preference.
For shorter focal lengths, a larger sensor and more pixel resolution would be better from the point of DoF control and detail resolution. FF is not big enough, really; what I want is the current "small" MFD: 33x44 mm @ 50 Mpixel seems almost ideal to me. That's about 4x the sensor area with 2x the resolution, so it has larger photosites with hopefully more dynamic range. This nets greater DoF control with shorter focal length lenses, along with the greater resolution that wide angle photography needs for capture of high resolution detail; and lenses in the 15 to 75mm range that are reasonably light, fast, and compact are not too difficult to make.
My ideal system would be two camera bodies of modest size, one with an APS-C sensor and one with a small-MFD sensor, and one set of lenses that covered both formats with focal lengths from about 15mm to about 300mm. That would net the most capable and flexible complete system for my photographic ideas. No such single system exists today, but I keep hoping. 😀
G