The 85 series, like the 80 82 and 81 series, are light balancing filters that transmit all colors. They merely alter the balance of the blue and red end of the spectrum. They will do almost nothing on B&W film.
The B&W contrast filters are band pass filters that totally block a portion of the spectrum while transmitting the rest of the spectrum reasonably efficiently.
The #21 was not a popular filter for normal photographic use "back in the day" when Series filters were common. The closest you are likely to find will be a #9 (aka K3) or #15 (aka "G"), both giving a slightly weaker effect, or a #25 (aka "A" or incorrectly a 25A) which would give a stronger effect. The #23A "light red" would be a good substitute, but is likely just as rare in series sizes.
Wikipedia has a good chart. Only those filters with a old style letter designation in addition to the modern number designation are likely finds in the old Series VI size.