Over the decades I have owned a Anscoflex, a Mamiya C3, a Rolleiflex 2.8E2, a Super Ricohflex, and just recently a Yashicamat. Every one of those were reliable but the Yashicamat which gave up the ghost on the third roll I put throug it. I do not think the problem was design, just an old camera that probably had a poor repair done to it sometime in the past (the front and crank side Vulcanite were a slightly different pattern than the rest; a sure sign that the camera had been worked on).
Based on those I like the ergonomics of the Rollei and the Yashica best. The Mamiya is a camera that belongs on a studio stand. The only thing wrong with the Automat style control setup, to me, is if you are using a handle mount flash, then one that can be focused with the right hand is nicer.
I also like the shutter/f-stop interlock my rollei had that everyone else seems to dislike. I kind of think that is a legacy of the Ansel Adams crap exposure system, which I hate even with a view camera. Why constantly fiddle with the exposure when the light has not changed a bit?
Also, to me, the reason to use a TLR is the waist level viewfinder, others claim they are unusable without a prism finder. Also, the optics are not all that far different on any of the cameras, an expert with a loupe can tell the difference, but it is kind of hard to see any on a normal print at the middle f-stops, if the lens is not damaged in some way.
A thing that improves the handling of most TLR's is a short shutter release cable. Most of the people I knew who shot TLR's back in the 40's & 50's always had one on the camera. You could wind the crank and set the shutter speed with out letting go of the cable release.
The rolleiflexes have one real problem, they are expensive as heck to have worked on, usually costing more than the lesser brands cost to buy. However, the fit, and finish on 50's era Rolleiflex are second to none. Strangely, as the technology improved later on the workmanship became worse.
In the end it is how you like the handling of the camera, followed by what you can afford. The rest is pretty much BS.