I have a C330 and a C220f -- and do so much prefer the C220f that I'm about to sell the C330.
But I'm comparing apples and oranges here: the C220f is the latest and much refined version and should be compared to a C330s, not to an earlier C330 or C330f. (Confusingly, there was no C220s.)
If you can, get either a C330s (quite rare and expensive, though) or a C220f (probably even rarer, but I got mine for 200€ with a 'blue dot' standard lens). The latest versions of the lenses, with a blue dot on the shutter lever, are supposed to be better (coated) than the earlier versions.
I do not think, by the way, that the C220 is so much lighter than the C330 that it make an important difference (but I use them on a monopad anyway). Your mileage may wary.
All in all great cameras and fun to use.