It seems to me that RF users (especially film RF users) are a rather diverse crowd that use rangefinders for a variety of reasons. You can see that in the way that this forum is divided on so many issues. Some love RFs for the small size and light weight. Some appreciate the manual controls. Some just love shooting film. Others like the build of the cameras, or the rangefinder focusing, and others are simply Leica junkies/snobs/aficionados. The x100 ticks many of the boxes that contribute to rangefinder appeal, so it is certainly likely that, if successful, it will steer some away from an RF that might have purchased one/contribute to some giving up on their RF. But it is neither a rangefinder-focusing camera nor is it a Leica, nor does it have interchangeable lenses, nor does it shoot film, so there are plenty of segments in the "RF user" group that won't be interested.
Meanwhile, I contend that most of the people that will buy an x100 *instead* of an RF would have been buying used anyway, so the effect on new product sales will be miniscule. The used markets may see some shifts, but nothing major.
I do expect the camera to be a big deal though, both among the community on this site and among hobbyists that may not have naturally found their way to RFs. I'm excited, both by the facts of the camera and by the way Fuji is treating it. I cannot remember a time when any company (even Leica) had this kind of enthusiastic and enthusiast-driven approach to marketing a camera. They know we're out here, and they want to sell us a camera. What more could you ask for?